Curcumin aids IBS-C treatmentTherapeutic effects of curcumin on constipation-predominant irritable bowel syndrome is associated with modulating gut microbiota and neurotransmitters.
Study compares curcumin with control
We examined the effects of curcumin, a compound derived from turmeric, on constipation-predominant irritable bowel syndrome (IBS-C). In our study, we used a rat model to better understand how curcumin might help alleviate the symptoms of this common condition, affecting many people worldwide.
To assess curcumin’s impact, we compared it with mosapride, a recognized treatment for IBS-C. We analyzed changes in gut microbiota and levels of key neurotransmitters involved in gut function, such as serotonin, substance P, and vasoactive intestinal peptide. Our findings revealed that rats treated with curcumin experienced notable improvements, including increased fecal weight and water content, and a faster transit rate in the small intestine.
Additionally, curcumin treatment lowered the serum levels of those neurotransmitters that are typically elevated in individuals with IBS-C. Our study suggests that the benefits of curcumin may stem from its ability to modify gut bacteria and affect these neurotransmitter levels, offering a promising avenue for managing IBS-C.
However, while we found significant improvements linked to curcumin, it’s essential to consider that the study also included comparisons with other treatments, which might complicate the understanding of curcumin’s isolated effects. Overall, curcumin could be a valuable option for those suffering from IBS-C, particularly when combined with other therapies.
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Turmeric-fennel oil improves IBS symptomsEfficacy of bio-optimized extracts of turmeric and essential fennel oil on the quality of life in patients with irritable bowel syndrome.
Combination effects complicate assessment
We set out to evaluate the impact of a natural treatment combining turmeric and essential fennel oil on patients suffering from irritable bowel syndrome (IBS), a condition that can severely affect daily life. Our study involved a total of 211 participants, including those with various IBS subtypes: diarrhea-predominant (IBS-D), constipation-predominant (IBS-C), and mixed (IBS-M).
Participants took Enterofytol®, which contains bio-optimized extracts of turmeric and fennel oil, for two months—starting with two capsules twice a day for the first month, followed by one capsule daily for the second month. Before and after this treatment period, we gathered data on symptom severity and quality of life.
What we found was quite promising. Across all IBS subtypes, patients reported a significant reduction in symptom severity and an improvement in their overall quality of life. Interestingly, while IBS-D patients initially had the most challenging symptoms, they also showed the most significant positive response to the treatment. We observed that the improvements were consistent, no matter the age or sex of the patients, highlighting the potential role of natural remedies like turmeric in managing IBS symptoms.
These results suggest an optimistic outlook for using turmeric and fennel oil as complementary therapies for IBS, enhancing patients' everyday well-being.
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Curcumin and fennel oil improve IBSCurcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome.
Moderate relevance to curcumin effects
We explored the effectiveness of a combination of curcumin and fennel essential oil in providing relief for patients suffering from Irritable Bowel Syndrome (IBS). In a randomized, controlled study involving 121 participants with mild-to-moderate IBS symptoms, we administered either the curcumin-fennel combination or a placebo over a 30-day period.
Our findings revealed that this unique blend significantly reduced the severity of IBS symptoms, as measured by a dedicated scoring system. Patients taking the curcumin-fennel oil experienced a robust improvement, particularly in abdominal pain and overall IBS symptom severity, with many reporting that they felt symptom-free by the end of the trial.
Moreover, quality of life metrics showed consistent improvement among participants using the curcumin-fennel oil compared to those who received the placebo. This suggests that not only does this combination help manage symptoms, but it also enhances daily living for those affected by IBS.
Overall, our study supports the potential benefits of integrating natural nutraceuticals like curcumin and fennel essential oil into treatment plans for IBS, offering a promising option for those seeking relief.
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Turmeric may aid IBS-C symptoms[Dry jelly concentrate with vitamins and dietary fiber in patients with IBS with constipation: a comparative controlled study].
Mix of ingredients complicates assessment
We conducted a study to explore the effects of a specially formulated dry jelly concentrate containing turmeric, alongside other ingredients like inulin and pyridoxine, on patients suffering from irritable bowel syndrome (IBS) with constipation. Our research involved fifty participants who met the Rome III criteria for IBS-C. They were divided into two groups: one received the jelly drinks along with a standard diet for two weeks, while the control group only adhered to the standard diet.
Throughout the study, we carefully recorded patients' responses to their treatment using various measures. We observed significant improvements in the group that consumed the jelly. They experienced better stool frequency and consistency, a reduction in abdominal pain, less bloating, and an enhanced sense of bowel emptying. Additionally, the quality of life for these patients showed a marked increase. In contrast, the control group saw only slight improvements in abdominal pain and bloating.
Importantly, we did not observe any significant adverse events during the treatment period, indicating that the jelly was safe for consumption. Overall, our findings suggest that the combination of turmeric, inulin, and pyridoxine can positively impact the symptoms of IBS-C, making it a potentially useful addition to dietary treatments for those affected.
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Turmeric may alleviate IBS symptomsTurmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study.
High relevance to turmeric IBS treatment.
We undertook an investigation to understand how turmeric, scientifically known as Curcuma longa, might affect symptoms of irritable bowel syndrome (IBS) in healthy adults. In a well-structured pilot study, we screened 500 volunteers for IBS and ultimately randomized 207 suitable candidates to assess the impact of taking one or two tablets of a standardized turmeric extract daily for eight weeks.
Throughout the study, we observed significant improvements in IBS symptoms. The prevalence of IBS symptoms decreased notably in both dosage groups, and after treatment, those taking one tablet saw a 53% reduction in symptoms, while the two-tablet group experienced a 60% decline. We also noted a meaningful reduction in abdominal pain and discomfort, with scores dropping by 22% and 25% respectively.
Furthermore, most participants reported improved overall quality of life related to their IBS symptoms. Approximately two-thirds of individuals noted a positive change in their symptoms post-treatment, indicating a favorable response to turmeric. While there were no significant differences between the two dosage groups, the findings confirm that turmeric may offer a helpful option for managing IBS symptoms.
Given these encouraging results, we believe that further placebo-controlled trials are necessary to validate the effectiveness of turmeric in treating IBS.
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